Cancer immunotherapy by a bacterial superantigen
نویسندگان
چکیده
منابع مشابه
Protection against bacterial superantigen staphylococcal enterotoxin B by passive vaccination.
We investigated the ability of two overlapping fragments of staphylococcal enterotoxin B (SEB), which encompass the whole toxin, to induce protection and also examined if passive transfer of chicken anti-SEB antibodies raised against the holotoxin could protect rhesus monkeys against aerosolized SEB. Although both fragments of SEB were highly immunogenic, the fragments failed to protect mice wh...
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Both superantigens (SAG) and many anti-TCR monoclonal antibodies (mAb) have specificity for the V beta region of the TCR encoded by TCRBV genes. For instance the bacterial SAG staphylococcal enterotoxin E (SEE), the retroviral SAG MTV-9 and the mAb OT145 each react with human T cells expressing BV6S7. This BV gene encodes two common alleles. We found that SEE and the mAb preferentially activate...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1991
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.14.528